Key Features

• Printed cell viability >95%.
• ± 10 um spatial accuracy and a volume range 700pL - 4uL
• 1536-well plate filled in <1 minute
• Systems can be configured for a wide range of applications: One channel for simple cell printing, 2-channel for multiple cell types or cell and reagent printing, and 4-channel for bulk dispensing of cells.
• Larger plate and deck formats are available to support both research and high throughput robotic integration.
• Multiple channels can be used for multiple cell lines. The CellJet supports multiplex assays without cross- contamination.
• Full control of dispense height and dispensing speed offers easy optimization, improved performance and faster results for a wide variety of cell types.
• Choice of drop-by-drop or on-the-fly dispensing modes for optimized performance and increased throughput.
• System dispenses a full range of cell types from robust to delicate.
• synQUAD technology is able to dispense fluid types from low viscosity solvent to highly viscous solutions such as 30% PEG. Ideal for protein/DNA suspensions or hydrogels.
• The CellJet includes a cover over each plate which creates a micro-environment for each cell to prevent contamination and evaporation. The cover is removable for easy cleaning and sterilization.
• The CellJet can fit into most standard fume hoods or can be purchased with an enclosed chamber with optional humidity control.
• Flexible, easy-to-use software offers productivity to multiple users with minimal training.

The CellJet Cell Printer incorporates Digilab’s proprietary synQUAD liquid dispensing technology that offers both on-the-fly and drop-by-drop non-contact cell printing while maintaining the viability of even the most delicate cells. This extremely flexible technology offers users full control over critical dispense parameters such as height of dispense and dispensing speed which allows printing of both viscous solutions and fragile cells.

The CellJet prints into plates or onto slides using a valve-free fluid path which greatly reduces cell damage. The printer also includes full wash capability, an easy-to-clean and sterilize evaporation cover and an effective instrument design for hassle-free maintenance.

Applications

• Stem cell research
• Cell sorting core facilities/FACS centers
• Live cell deposition and printing
• Stem cell cloning and manipulation
• Live cell arrays
• Live cell layering with or without matrixes
• Live cell assays
• Cell migration assays – Pharma scratch tests
• Cell differentiation assays
• Tissue construction in vitro
• Tissue engineering & scaffold construction

More Information

• Application of CellJet technology for precise "printing" of adherent mammalian cells with no loss of viability

• Application of CellJet technology for precise "printing" of mammalian cell lines grown in suspension

• Precise Dispensing with no Loss in Viability - Human Muscle Stem Cell

• Smooth Muscle Cells: Use of CellJet Technology for Precise Dispensing with no Loss in Viability
• Bioprinting Human Mesenchymal Stem Cells Using the Celljet
• Bioprinting Human Mesenchymal Stem Cells Suspended in Alginate in Patterns Using the CellJet Without Loss in Cell Viability

Key Features:

• Non-contact deposition
• Features as small as 5 μm
• Viscosities up to 450 cP
• True contiguous lines, arcs, and bends
• Microstructure fabrication
• Consistent spot size and shape with coefficients of variability as low as 10%
• 3-axis positioning with 5 μm resolution
• Integrated digital video capture
• Automated surface calibration

• Rapid prototyping
• Graphene/ carbon nanotube printing
• Additive repair
• Polymer microstructure fabrication
• pOLED printing
• High-density protein microarrays
• Patterning of live cells

The GIX Microplotter II utilizes the same innovative technologies as the Microplotter Desktop and the Microplotter to deposit fluid in a non-contact manner to form single droplets or contiguous lines, arcs or bends. These are uniform elements and are not constructed from overlapping droplets like other technologies. This makes the Microplotters particularly well-suited to the polymer electronics field. The Microplotter II offers consistent spot size and shape with coefficients of variability as low as 10% and 3-axis positioning with 5 μm resolution.

• Deposition of catalyst for carbon nanotube growth
• Drawing a polymer-based blue LED
• Mass spectrometry enhancement through small spots
• Printing lines of nanometallic ink for conductive electronic traces
• Spotting DNA at a high resolution for microarray fabrication
• Spotting proteins for an ELISA-type microarray assay

Key Features

• Non-contact deposition
• Features as small as 5 μm
• Viscosities up to 450 cP
• True contiguous lines, arcs and bends
• Microfeature printing
• Consistent spot size and shape with coefficients of variability as low as 10%
• 3-axis positioning with 20 μm resolution
• Integrated digital video capture

• Rapid prototyping
• Macro-electronics printing
• Protein microarrays
• Patterning of live cells.

The core of the Microplotter Desktop is a dispenser that uses controlled ultrasonics to deposit fluids in a non-contact manner. This patented technology can produce picoliter droplets that form features on a surface as small as 5 μm wide. When combined with automatic surface height calibration, coefficients of variability for deposited feature diameters as small as 10% can be achieved. A wide range of fluids can be used, including aqueous solutions and many organic-solvent-based mixtures. Fluids that other dispensers struggle with, such as saturated solutions for MALDI-TOF matrices, or fluids with viscosities up to 450 cP, can be deposited with ease. The ultrasonic pumping action is also an efficient cleaning mechanism for quickly depositing many solutions sequentially.

• Deposition of catalyst for carbon nanotube growth
• Drawing a polymer-based blue LED
• Mass spectrometry enhancement through small spots
• Printing lines of nanometallic ink for conductive electronic traces
• Spotting DNA at a high resolution for microarray fabrication
• Spotting proteins for an ELISA-type microarray assay